Boronic acid derivatives
Cayman Chemical CAY10499, Purity: ≥98%, CAS: 359714-55-9, 10 mg
A non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively); inhibits ATGL, DAGLa, ABHD6, and CES1 at 5 mM; inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 µM, respectively); reduces FRUC diet- and AIN-93M diet-induced increases in cytosolic lipase activity in rats
Cayman Chemical KT 5720 Inhibitors
A potent inhibitor of PKA; blocks PKA signaling through competitive inhibition of ATP (Ki = 60 nM); inhibits phosphorylase kinase, PDK1, MEK, MSK1, PKBα, and GSK3β
Cayman Chemical CAY10485, Purity: ≥98%, CAS: 615264-62-5, 50 mg
An ACAT-1 and -2 inhibitor with antioxidant activity; inhibits human ACAT-1 and ACAT-2 (IC50s = 95 and 81 µM, respectively); inhibits cooper-mediated oxidation of LDL by 91% at 2 µM
Aobchem 3-(2-Bromophenylcarbamoyl)phenylboronic acid | ≥97% | CAS 874288-30-9 | C13H11BBrNO3 | 10g
3-(2-Bromophenylcarbamoyl)phenylboronic acid | ≥97% | CAS 874288-30-9 | C13H11BBrNO3 | 10g
Aobchem 4-Ethoxy-3-fluorophenylboronic acid | ≥97% | CAS 279263-10-4 | C8H10BFO3 | 10g
4-Ethoxy-3-fluorophenylboronic acid | ≥97% | CAS 279263-10-4 | C8H10BFO3 | 10g
Aobchem 2-Fluoro-5-methylboronic acid | ≥97% | CAS 166328-16-1 | C7H8BFO2 | 25g
2-Fluoro-5-methylboronic acid | ≥97% | CAS 166328-16-1 | C7H8BFO2 | 25g
Aobchem 4-Chloro-3-fluorophenylboronic acid pinacol ester | ≥95% | CAS 627525-83-1 | C12H15BClFO2 | 10g
4-Chloro-3-fluorophenylboronic acid pinacol ester | ≥95% | CAS 627525-83-1 | C12H15BClFO2 | 10g
Aobchem 2-Butoxy-5-fluorophenylboronic acid | ≥97% | CAS 480438-62-8 | C10H14BFO3 | 1g
2-Butoxy-5-fluorophenylboronic acid | ≥97% | CAS 480438-62-8 | C10H14BFO3 | 1g
Aobchem Thiophene-3-boronic acid pinacol ester | ≥95% | CAS 214360-70-0 | C10H15BO2S | 5g
Thiophene-3-boronic acid pinacol ester | ≥95% | CAS 214360-70-0 | C10H15BO2S | 5g
Aobchem 2 4-Dimethoxyphenylboronic acid | ≥97% | CAS 133730-34-4 | C8H11BO4 | 25g
2 4-Dimethoxyphenylboronic acid | ≥97% | CAS 133730-34-4 | C8H11BO4 | 25g
Aobchem 2 6-Dichlorophenylboronic acid | ≥97% | CAS 73852-17-2 | C6H5BCl2O2 | 25g
2 6-Dichlorophenylboronic acid | ≥97% | CAS 73852-17-2 | C6H5BCl2O2 | 25g